arrayMagic: two-colour cDNA microarray quality control, preprocessing

arrayMagic: two-colour cDNA microarray quality control and preprocessing

Summary: arrayMagic is a software package for quality control and preprocessing of two-colour cDNA microarray data. The automated analysis pipeline comprises data import, normalization, replica merging, quality diagnostics and data export. The script-based processing combines reproducibility and flexibility at high-throughput and provides quality-assured and preprocessed microarray data to high...

Weighted analysis of paired microarray experiments.

In microarray experiments quality often varies, for example between samples and between arrays. The need for quality control is therefore strong. A statistical model and a corresponding analysis method is suggested for experiments with pairing, including designs with individuals observed before and after treatment and many experiments with two-colour spotted arrays. The model is of mixed type w...

Package ‘ TwslmSpikeWeight ’ April 17 , 2009

April 17, 2009 Version 1.0.1 Date 2006-01-17 Maintainer Deli Wang Author Deli Wang, Jian Huang Depends splines Title Systematic approaches using TW-SLM for incorporating control spots and data quality information to improve normalization of cDNA microarray data. Description TwslmSpikeWeight is for normalization of cDNA microarray data with the two-way semilinear model(TW...

cDNA Microarray Data Normalization

Grow-Cut Based Automatic cDNA Microarray Image

Complementary DNA (cDNA) microarray is a well-established tool for simultaneously studying the expression level of thousands of genes. Segmentation of microarray images is one of the main stages in a microarray experiment. However, it remains an arduous and challenging task due to the poor quality of images. Images suffer from noise, artifacts, and uneven background, while spots depicted on ima...